منابع مشابه
Liposomal drug delivery in multimodal cancer therapy
Encapsulating cytostatics into lipid vesicles, i.e. liposomes, improves tumour drug accumulation and reduce adverse effects. Liposomal doxorubicin (DXR) has been used in the treatment of a variety of cancers and may also be suitable for combining with other treatment modalities. By modulating liposomal membranes, liposomes can be made ultrasound (US) sensitive releasing encapsulated drug in tum...
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Almost from the time of their rediscovery in the 60's and the demonstration of their entrapment potential, liposomal vesicles have drawn attention of researchers as potential carriers of various bioactive molecules that could be used for therapeutic applications in humans and animals. Several commercial liposome-based drugs have already been discovered, registered and introduced with great succ...
متن کاملLiposomal drug delivery systems--clinical applications.
Liposomes have been widely investigated since 1970 as drug carriers for improving the delivery of therapeutic agents to specific sites in the body. As a result, numerous improvements have been made, thus making this technology potentially useful for the treatment of certain diseases in the clinics. The success of liposomes as drug carriers has been reflected in a number of liposome-based formul...
متن کاملImaging of liposomal drug delivery systems by atomic force microscopy
Over the past four decades, the research focused in the development of new liposomal drug delivery systems exponentially grew as a result of their proven efficacy in carrying pharmacological active molecules to target specific sites. In fact, the drug loading into liposomes both increases the drug’s bioavailability through the prevention of unfavourable chemical reactions triggered by enzymatic...
متن کاملLiposomal delivery systems for intestinal lymphatic drug transport
Intestinal lymphatic drug delivery has been widely studied because drugs can bypass the first-pass metabolism in the liver via the lymphatic route, which increases oral bioavailability. Various lipid-based nanoparticles have been used to deliver hydrophobic drugs to the lymphatic pathway. This review focuses on the liposomal delivery systems used for intestinal lymphatic drug transport. Liposom...
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ژورنال
عنوان ژورنال: AACR Education book
سال: 2015
ISSN: 1943-6475
DOI: 10.1158/aacr.edb-15-8186